[Nathan Fillion, who moves from the bridge of the spaceship Serenity to the science-fiction horror movie Slither , told SCI FI Wire that the latter will be a return to old-fashioned splatter films.] There's stuff blowing up. There's some nasty [stuff]. There's some sliming, ... There's a lot of prosthetics. We leaned away from the CGI and leaned towards the prosthetics as an homage to the horror movies of yesteryear. Our creator/director, James Gunn, said it will be the last time he ever does that.